siRNA

siRNA Technology and Applications: "Small interfering RNA (siRNA) is a tool that is revolutionizing bioscience research. The increased use of siRNA in peer reviewed publications clearly demonstrates that it is an incredibly powerful means to specifically knock-down a gene's message, and subsequently the protein level of the targeted gene. In this manner, cellular-based assays can be conducted in the absence and presence of the targeted gene's protein.

The value of such an experiment has long been known as researchers the world over have employed genetic knock-out technologies, dominant negatives and chemical inhibitors of protein activities to perform such experiments. The use of siRNA is replacing all three of these methodologies."